Outside a hut in a Vietnam Jungle, a couple notices something which makes the wife scream. Later, Klaus Starr arrives to the scene, where tourists and locals gawk at a flying pig.
In New Orleans, Jesse, Cassidy, and Tulip check the last Jazz club but fail to find God. Jesse begins to have second thoughts and Cassidy suggests they take a break. The three then head for the Hurt Locker, and Tulip volunteers her "boyfriend", Cassidy. Tulip picks the biggest gun and a man shoots it at Cassidy, who's wearing a bulletproof vest. After pretending Cassidy died, the patrons flee the area. Tulip feeds Cassidy blood and the three steal the money at the bar while spending the night there.
Jesse assured Tulip that the Saint of Killers is gone and not to worry about him. Meanwhile, a French professor explains to Cassidy that Denis is dying and wants Cassidy's help to have an eternal life, which Cassidy quickly denies.
Back in Vietnam, Klaus Starr calls an associate and asks for several well equipped operatives before thinking of another solution.
In a flashback, Klaus Starr is interviewed for the Grail. During this, he expressed how he wishes to clean the world of parasites that befoul society.
Tulip wakes from a nightmare involving the Saint of Killers. She goes out and boils water on a kettle. Shortly after, she bumps into the Saint of Killers who shoots her, though it was another nightmare. After she wakes up, she explains her nightmares. Tulip asks if Jesse feels something isn't right but Jesse leaves to speak to a doomsday preacher.
At a morgue, Cassidy wakes up, realizing he was mistaken to have been dead.
In another flashback, Klaus Starr and several other candidates go through rigorous trials for the Grail. Klaus effortlessly goes through the trials, before killing the remaining competitor, earning himself a spot on the Samson Unit of the Grail. Saltonstall explains the Grail's mission and that Jesus had a child and the Grail had been protecting his bloodline for millenniums. Shortly after, Klaus pushes Saltonstall over his office.
A morgue worker apologizes to Cassidy for the misunderstanding. Cassidy then notices a family mourning over a dead person.
Tulip returns to the Hurt Locker and explains they conned them and challenges them to win their money back. As she is shot, she envisions a shooter as the Saint of Killers and quickly gets up. She then prompts them to shoot her again.
Jesse speaks to the doomsday preacher about the end of the world. He then explains of a parishioner that gave up a fragment of his soul to save a friend, but is told the parishioner should have given up a kidney instead.
Back in Vietnam, Klaus stands over the flying pig, which had been killed, along with the entire village. He is called by an associate, who tells him to go to New Orleans for his next mission, involving Jesse Custer.